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Rabies Testing

Rabies testing is available at the State Public Health Laboratory on a daily basis. The laboratory does more than 2000 specimens annually from across the state of Missouri. Animals suspected of having rabies infection may be submitted for testing through a veterinarian, local or county health department office, district health representative, or other health care provider.

Shipping containers are provided by the laboratory for the transport of animal specimens. A free courier service is provided for the transportation of specimens to the laboratory. You may contact your local county health agency or contact us for courier information. Do not ship animal heads without obtaining proper shipping containers and instructions. Do not ship rabies boxes by UPS or the U.S. Postal Service. Specimens may be delivered directly to the laboratory if courier delivery is unavailable. 

Rabies specimens should be submitted for testing through a veterinarian, local or county health department office, district health representative, or other health care provider. Shipping containers and instructions are supplied by the laboratory. Do not ship animal heads without obtaining proper shipping containers and instructions.

New Rabies Box

The State Public Health Laboratory is supplying a certified rabies mailer that meets the Infectious Disease regulations required by the Department of Transportation. It is very important that this mailer be used in its entirety, including the enclosed documentation and labeling. Please to not alter or discard any component of the mailer. This mailer is provided for the protection of your staff, the courier service, and laboratory employees. The submitting facility is responsible for any fines that could be incurred because of failure to follow shipping guidelines as detailed in the mailer.

List of Contents:

  • Test Request Form (pdf)
  • Diagnostic Specimen (Animal Matter)
  • Absorbent packet
  • Inner Protective cover
  • Screw-top pail with threaded cover
  • Foam Cooler w/lid
  • Test request form
  • Instruction sheet
  • Gel pack/Refrigerant

The boxes are identified by a four-digit code written on the side of the box. After use, the box will be returned to the facility identified by he number. If you wish to receive mailers for your facility, contact us.

Packaging Instructions

DOT RSPA Web Site http://www.myregs.com/dotrspa [(CFR49) 173.196 and 172.204]

Specimen Guidelines

  • Avoid damage to the brain. Do not shoot or crush the skull.
  • Have a qualified individual remove the animal head from the body. Do not ship whole animals except for bats and small rodents.
  • Package the animal head so that it does not leak. Allow excess blood to drain before placing the head in the shipping container.
  • Use ONLY freeze packs as refrigerant in the shipping container. Never put ice in a rabies mailing container.
  • Fill out the laboratory form and return it to the enclosed envelope. Please include your phone number and mailing address.
  • Do not use staples on the laboratory form or envelope.
  • If submitting only tissue samples, please ensure that an adequate specimen is collected. The laboratory must receive a full cross-section of the brain stem and either the cerebellum or hippocampus. Contact the laboratory before collecting tissue samples.
  • Rabies samples should be kept refrigerated until submitted for testing. Freezing is not recommended, but will NOT affect the test results. Repeated freeze-thaw cycles should be avoided.

Failure to follow proper procedure may cause delays in testing, resulting in spoilage of animal brain tissue and unnecessary vaccinations.

Specimen Acceptability

Specimens for rabies testing will only be accepted when there is known or potential exposure of any of the following to a possibly infected animal:

  • Humans
  • Animals maintained as pets
  • Domesticated animals
  • Exotic or non-native animal species maintained for husbandry purposes or in zoos

Specimens for rabies testing will not be accepted in the following instances:

  • Animals (including bats) when there has been no exposure history as described above
  • Decomposed or destroyed brains (when testing material is unavailable)

Rodents:

  • The laboratory will not accept domesticated (caged) mice, rats, gerbils, hamsters, or guinea pigs for rabies testing, regardless of exposure history.
  • Wild rodents will be accepted and tested when human exposure (biting) has occurred 
    Any exception to this policy must be authorized by the laboratory.

Diagnosis of Rabies in Humans

Specimens for rabies diagnosis in humans must be cleared by the central laboratory in Jefferson City. After obtaining instructions and a laboratory identification number, the clinical specimens will be shipped directly to the Centers for Disease Control in Atlanta. 

Human specimen submission requirements (CDC):

Links to More Information