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Common Opportunistic Infections in HIV/AIDS

African Americans and HIV/AIDS

Candidiasis
Also known as: Thrush
Caused by: Candida albicans (fungus)
May Affect: Mouth, esophagus (throat), gut, anus, vagina, skin (rashes)
Symptoms: Oral thrush causes loss of taste and appetite, dry mouth; esophageal causes dysphagia (difficulty swallowing).
Clinical Comments A diagnosis of thrush doesn't mean that the patient has AIDS, but may suggest that the virus is progressing. T-cell range: Under 350
Cryptosporidium enteritis
Also known as: Crytosporidiosis
Caused by: Cryptosporidium (parasite)
May Affect: Gastrointestinal tract (colon)
Symptoms: Watery diarrhea several times a day; abdominal cramping; nausea; malaise (general ill feeling); malnutrition and weight loss
Clinical Comments No reliable treatment exist for treatment, the best approach is to improve the immune status of the individual in addition to supportive treatment for symptoms.
Cryptococcal Meningitis
Also known as:  
Caused by: Cryptococcus neoformans (fungus/yeast)
May Affect: Brain
Symptoms: Fever, headache, nausea and vomiting, confusion, sensitivity to light
Clinical Comments In order to diagnosis cryptococcal meningitis a lumbar puncture (spinal tap) must be performed. T-cell range: Under 100
Cytomegalovirus
Also known as: CMV
Caused by: Cytomegalovirus (herpes-like virus)
May Affect: Eyes (Retinitis), Brain, Lungs (Pneumonia), Gut (Gastroenteritis)
Symptoms: Blindness, confusion, dyspnea (difficult or labored breathing), ulcers, diarrhea, abdominal pain, fevers
Clinical Comments CMV is a common infection, but causes significant complications among people that have immune suppression and lifetime maintenance may be required. T-cell range: Under 50
Dementia and Nervous System Problems
Also known as: AIDS Dementia Complex
Caused by: Advanced HIV infection
May Affect: Brain
Symptoms: Loss of memory, affect, coordination, hallucinations, insomnia, personality changes
Clinical Comments Diagnostic of AIDS even if no concurrent infection. T-cell range: Under 100
Herpes Zoster
Also known as: Shingles
Caused by: Herpes simplex Type I or II (virus)
May Affect: Mouth, skin, lungs, gastrointestinal tract (colon), brain, anal or genital areas
Symptoms: Pain, skin lesions, confusion
Clinical Comments HIV does not cause shingles, but more frequent/severe herpes outbreaks are likely among individuals with HIV. T-cell range: Under 350
Human Papillomavirus
Also known as: HPV; Genital Warts
Caused by: Human papillomaviruses (virus)
May Affect: Genitals
Symptoms: Raised flesh-colored lesions on the genitals, anus, or surrounding skin; cauliflower-like growth around the anus or genitals; increased dampness or moisture in the area of growths; itching; increased vaginal discharge; abnormal vaginal bleeding; dysplasia (abnormal changes in the cell lining of the cervix).
Clinical Comments There is a strong link between anal and cervical cancer.
Kaposi's Sarcoma
Also known as: KS
Caused by: Human Herpesvirus - 8 (HHV-8)
May Affect: Skin, mouth, many internal organs (lungs, liver, brain, gut)
Symptoms: None at all, or dyspnea (difficult or labored breathing), abdominal pain, or visible bluish-red lesions.
Clinical Comments Reoccurrence can occur even after apparent successful treatment.
AIDS-related Lymphoma
Also known as: Hodgkin's and Non-Hodgkin's Lymphoma
Caused by: Cancer (malignant) cells in the lymph system.
May Affect: Liver, bone marrow, brain, spleen, lymph nodes
Symptoms: AIDS-related lymphoma usually grows faster and spreads outside the lymph nodes and to other parts of the body more often than lymphoma that is not related to AIDS. Because therapy can damage weak immune systems even further, patients who have AIDS-related lymphoma are generally treated with lower doses of drugs than patients who do not have AIDS.
Clinical Comments A diagnosis of thrush doesn't mean that the patient has AIDS, but may suggest that the virus is progressing.
Molluscum
Also known as:  
Caused by: Molluscipoxvirus Molluscum contagiosum
May Affect: Skin
Symptoms: Raised painless skins lesions found on the genitals, abdomen, or inner thigh of adults.
Clinical Comments In people diagnosed with AIDS a rapid worsening case of molluscum may form.
Mycobacterium Avium Complex
Also known as: MAC or MAI
Caused by: Mycobacterium avium intracellulare (mycobacterium)
May Affect: Lungs, bone marrow, liver, intestine, brain, skin, usually disseminated in the blood
Symptoms: Severe fever, chills, bone and/or abdominal pain, weight loss, weakness, anemia, night sweats
Clinical Comments Similar to Tuberculosis but is not contagious, T-cell range: Under 75
Pneumocystis carinii Pneumonia
Also known as: PCP
Caused by: Pneumocystis carinii (fungus)
May Affect: Lungs (pneumonia)
Symptoms: Cough, fever, shortness of breath, difficult or labored breath
Clinical Comments This fatal pneumonia is frequently prevented with a prophylaxis (preventive medicine) once a person is diagnosed with AIDS. T-cell range: Under 200
Progressive Multifocal Leucoencephalopathy
Also known as: PML
Caused by: JC virus
May Affect: Brain
Symptoms:

Loss of coordination, clumsiness, memory loss, progressively worsening of the legs, and to a lesser extent the arms;

Aphasia (impairment of speech), visual field defects, and headaches
Clinical Comments T-cell range: Under 100
Toxoplasmosis
Also known as: Toxo
Caused by: Toxoplasma gondii (protozoan)
May Affect: Brain (Encephalitis -inflammation of the brain), eyes (Retinitis - inflammation of the retina), heart, or liver
Symptoms: Enlarged lymph nodes in the head and neck, headache, sore throat, muscle pain, blurred vision, seizures, stroke-like symptoms
Clinical Comments Lifelong maintenance required. T-cell range: Under 100
Tuberculosis
Also known as: TB; Consumption
Caused by: Mycobacterium tuberculosis
May Affect: Lungs, bone marrow, liver, intestine, brain
Symptoms: Severe fever, chills, bone and/or abdominal pain, weight loss, weakness, coughing up blood, night sweats
Clinical Comments Without the aid of an active immune system, treatment is more difficult and the disease is more resistant to therapy. T-cell range: Under 350
AIDS Wasting Syndrome
Also known as: Wasting Syndrome
Caused by: Advanced HIV infection
May Affect: Body
Symptoms: Extreme weight loss and anorexia; chronic diarrhea, weakness, fever
Clinical Comments T-cell range: Under 100

In addition to the above-mentioned opportunistic infections, which occur because of a weakened immune system, the following are perceived results of advanced HIV infection.

Organ Symptoms
Skin

Eczema, Seborrhea (increased oily skin), fungus infections, Folliculitis (inflammation of hair follicles), Shingles

Mouth and Throat Hairy leukoplakia (immovable white patch of mucous membrane.), apthous ulcers (canker sores.), gingivitis (inflammation of the gums), periodonitis (disease that attacks gums and bone around the tooth.)
Nose and Sinuses Frequent sinusitis that is mostly bacterial, occasionally fungal
Heart Cardiomyopathy (deterioration of the heart muscle)

Gastrointestinal tract (colon)

Poor nutrient absorption, wasting, esophageal ulceration, liver or gallbladder involvement.
Lungs Frequent/recurrent bacterial infections
Bone marrow (connective tissue inside the bones) Anemia, thrombocytopenia (low counts of blood platelets), and/or neutropenia (low counts of a specific white blood cell).

Sources:
MedlinePlus - a service of the US Library of Medicine and the National Institutes of Health
http://www.nlm.nih.gov/medlineplus/

Medical Encyclopedia: AIDS
http://www.nlm.nih.gov/medlineplus/ency/article/000594.htm

AIDSInfonet.org - Fact Sheet 500 Opportunistic Infections
http://www.aidsinfonet.org/articles.php?articleID=500